Mexican beaded lizard

A protein in its venom helped develop a diabetes drug that aids in regulating blood sugar levels

Adam Fagen


Mexican beaded lizard

EXEWCRENVUNTLCDDNE

A protein in its venom helped develop a diabetes drug that aids in regulating blood sugar levels

Population

One of the few truly venomous lizards in the world and one of Mexico’s most fascinating reptiles. Native to the Pacific coast of Mexico and parts of Guatemala, this mysterious, slow-moving lizard often gets mistaken for a Gila monster, its close cousin. But the Mexican beaded lizard is larger, darker, and adapted to different habitats — from tropical dry forests to scrublands and rocky outcrops. It is a secretive creature, mostly active during the evening or early morning, and spends much of its life hidden underground or among rocks.

Its most distinctive feature is its thick, beaded skin, covered in bumpy, bead-like scales called osteoderms, which feel almost like pebbled leather. These scales aren’t just for show — they offer tough protection against predators and rough terrain. The lizard is usually black or dark brown, with light yellow or cream markings forming bands or patches across its body. Its broad head, muscular limbs, and short tail give it a powerful, heavy appearance.

What sets the Mexican beaded lizard apart is its venom, which it delivers through grooved teeth in its lower jaw. Unlike venomous snakes that inject venom quickly, this lizard chews slowly, allowing the venom to seep into wounds. The venom is not usually deadly to humans, but it causes intense pain and swelling.

Despite its fearsome look, the Mexican beaded lizard is actually shy and non-aggressive, preferring to retreat rather than fight. Bites are rare and usually happen only when the animal is provoked or handled. Another cool behavior is its ability to store fat in its tail, which helps it survive long periods without food, especially during the dry season. It uses its strong sense of smell, thanks to a tongue-flicking motion similar to snakes, to track prey and navigate its surroundings.

Distribution

Country
Population est.
Status
Year
Comments
Mexico
LC
2021

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Terrestrial / Aquatic

Altricial / Precocial

Polygamous / Monogamous

Dimorphic (size) / Monomorphic

Active: Diurnal / Nocturnal

Social behavior: Solitary / Pack / Herd

Diet: Carnivore / Herbivore / Omnivore / Piscivorous / Insectivore

Migratory: Yes / No

Domesticated: Yes / No

Dangerous: Yes / No